Fri., Nov. 8, 2024
8:45am – 10:45am (2 CE hrs)
Room 101-B
Speaker: Effie Ioannidou, DDS, MDS
Robert J. Genco Distinguished Speaker Series
Recommended for: Everyone
Oral-systemic connections with relevance in both clinical practice and research
1. Impact of Oral Health on Systemic Diseases
-Review of existing evidence linking periodontal health to systemic conditions (e.g., cardiovascular disease, diabetes, kidney disease).
2. Personalizing Periodontal Interventions
-The role of individual patient factors (sex, genetics, comorbidities) in customizing treatment strategies.
3. Interdisciplinary Collaboration for Better Outcomes
-Importance of collaboration between dental and medical professionals in optimizing care for patients with oral-systemic connections.
-Incorporating routine oral health assessments into medical care for early detection and management.
Challenges in reporting quality and research gaps in oral-systemic health
1. Current Gaps in Research Reporting
-Inconsistencies in reporting outcomes in oral-systemic research and challenges related to transparency and reproducibility in randomized controlled trials (RCTs).
2. OHStat Guidelines and SAGER Compliance
-Overview of the OHStat guidelines for improving transparency in reporting clinical research data in oral health.
-SAGER Guidelines: Importance of adhering to the SAGER (Sex and Gender Equity in Research) guidelines to ensure accurate reporting on sex and gender as biological variables in clinical studies.
Conclusion and Shaping the Future
-Final thoughts on advancing personalized care and future research directions in oral-systemic health.
Learning Objectives:
1. Understand the Connection Between Oral and Systemic Health:
Gain a comprehensive understanding of how periodontal diseases impact systemic conditions, including cardiovascular disease, diabetes, and chronic kidney disease.
2.Improve Reporting Quality Using OHStat and SAGER Guidelines:
Learn how to apply the OHStat guidelines for standardized reporting and SAGER guidelines for sex and gender inclusion to enhance the transparency and reproducibility of oral-systemic research.
3. Tailor Clinical Interventions Based on Individual Factors:
Explore how personalized treatments based on patient-specific factors can optimize oral and systemic health outcomes, particularly in populations with chronic diseases.
Effie Ioannidou, DDS, MDS is a clinician scientist with training in Periodontology. Her research addresses clinical and translational questions on the anti-inflammatory effect of periodontal interventions in systemic health and chronic kidney disease. She has recently led a multicenter team of investigators to explore systemic antibiotic prescribing patterns in combination with periodontal therapy. By leveraging advanced molecular techniques, her team aims to advance the field and provide evidence-based guidance for clinicians, ultimately leading to more effective and sustainable periodontal treatment outcomes. By addressing the antibiotic stewardship priorities outlined by the NIH and the CDC, her lab produced preliminary data suggesting that antibiotic treatment leads to a microbial shift towards healthier communities, supporting the underlying hypothesis. Her team recently showed that systemic antibiotics are widely prescribed during initial periodontal treatment without clinical practice guidelines related to adjunct antibiotics. Recently, her team developed a new line of research focusing on the intersection of sex and gender in oral inflammatory diseases. They have produced data that highlights the lack of adherence to reporting guidelines as it pertains to sex and gender in RCTs in periodontology. Therefore, her lab is focusing on better understanding sexual dimorphism in periodontitis to explain disease disparities. Dr. Ioannidou is passionate about rigor and transparency in clinical research and is a proponent of high-quality scientific reporting and clinical trial registration.
Dr. Ioannidou is a founding member of the IADR Women in Science Network. She served as the Associate Editor of the JDR Clinical and Translational Research until June 2023. She is currently the AADOCR President-elect (2022-2026). She has served as an ADA Council on Scientific Affairs member. She is the Task Force on Design and Analysis in Oral Health Research’s Executive Director on Design and Analysis in Oral Health Research. She is an AADOCR (2018) and AAAS (2022) Fellow. Since July 1st, 2023, Dr. Ioannidou has served as the Editor-in-Chief of the two AAP Journals: Journal of Periodontology and the Clinical Advances in Periodontics.
Dr. Ioannidou is not associated with, employed by, nor consults for any manufacturer, supplier, or retailer of dental instruments or materials.
